Phenolic Acids, Flavonoids, and Antioxidant Properties of an Algerian Medicinal Astragalus Plant
Acides phénoliques, flavonoïdes et propriétés antioxydantes d'une plante médicinale d'astragale algérienne
Keywords:
Astragalus, Phenolic acids, Flavonoids, Antioxidant activity.Abstract
This work is devoted to the phytochemical and biological study of a medicinal plant belonging to the Algerian flora astragalus genus. This research was conducted to assess the phytochemical composition of methanolic extract using LCESIMS:MS ,following by testing in vitro antioxidant ability using DPPH and ß-caroten assays.
The liquid chromatography results showed that methanolicextract identified the presence of sixteen bioactive compoundsof the type phenolic acids and flavonoids.Rutin detected asmajor flavonoid with a concentration 6388.6090 mg/ml. And shikimic acid was detected as major phenolic acid with aconcentration 325.9176 mg/ml.Moreover the result of totalcontent of polyphenols and flavonoids 175.83±1.95 µgGAE/mg extract and 43.10±0.27 µg EQ/mg extractrespectively.concerning antioxidant activity the methanolicextract has a good activity in all tests used with IC50 of DPPH ,ß-caroten tests IC50=3.74±1,04 µg/ml and 4.64±0.62µg/mlrespectively.Indeed , the presence of phenolic compounds maycontribute to their antioxidant activity.
Keywords:Astragalus, Phenolic acids, Flavonoids, Antioxidant activity.
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